An overview about creatinine

creatinine TEST
creatinine TEST

What is it?

Creatinine is a waste product that is filtered through the kidneys and secreted out along with urine.

Synthesis:

  • It’s production involves creatine and phospho-creatine. Creatine is also synthesized endogenously by the liver, after methylation of glycocyamine. It is then transported to muscles and brain.
  • In muscles, it goes through a phosphorylation reaction and converts into phospho-creatine. Whenever your muscles goes through some wear and tear process, or involved in high intensity exercise, there metabolism produces creatinine.
  • Excess creatine in your diet; that is not utilized by body, also converts to creatinine.
  • During cooking, heat also causes creatine to produce creatinine.

Ranges:

  • Serum creatinine:

For males: 0.7 to 1.2 mg/dL.

For females: 0.5 to 1.0 mg/dL.

  • Urine creatinine (24 hour sample):

For males: 123.8 to 229.8 µmol/kg/day.

For females: 97.2 to 176.8 µmol/kg/day.

(Ranges may vary a little according to laboratories. Consult your doctor for the better understanding of your test result).

  • Men have high ranges because they have greater muscle mass.
  • A high value of it in serum might indicate that your kidneys are not functioning properly. But it just gives a clue; which might be wrong in some cases because, a person’s serum creatinine might be high because he has ingested high food sources of it or maybe he ended up doing high intensity work-out.
  • To be sure about your kidney’s health, always look for its glomerular filtration rate.

Major food sources:

  1. Beef.
  2. Salmon.
  3. Tuna.
  4. Red meat.
  5. Sushi.
  6. Sashimi.
  7. Pork.
  8. Herring.
  9. Liver.
  10. Chicken.
  11. Code.
  12. Sole.

Pointers that can help you maintain your creatinine levels:

  • The key is to improve your GFR (Glomerular Filtration Rate).
  • Try to detoxify your body daily, through natural sources.
  • Avoid high intensity exercises.
  • Add more fibrous foods to your diet.
  • Cut back on proteins.
  • Dehydration can also cause an increase in the levels.
  • Some researchers also support the use of chitosan, chamomile tea, stinging nettle, barley water, dandelion root, chinese rhubarb, cinnamon, sage, siberian ginseng, corn silk and astragalus because of their detoxifying and other kidney friendly properties. You should use them only after consultation.